As the cabinet reshuffle gets underway, Alan Johnson is set to replace Jacqui Smith as home secretary.
The health secretary will move to the home affairs brief as Gordon Brown seeks to reassert his authority.
The Department for Innovation, Universities and Skills is set to be abolished, with responsibilities split between Lord Mandelson's business department and Ed Balls's schools department.
John Denham, previously secretary of state at DIUS, moves to take over communities and local government.
John Hutton steps down as defence secretary and is replaced by Bob Ainsworth.
Sir Alan Sugar becomes 'enterprise tsar' with an appointment to the House of Lords.
Alistair Darling remains as chancellor, despite speculation that children's secretary Ed Balls would replace him.
After James Purnell's resignation, Yvette Cooper may take over at the Department for Work and Pensions.
Jack Straw stays in post as justice secretary, and Jim Murphy remains as Scotland secretary. Likewise, Ed Miliband with retain his position as environment secretary.
But the reshuffle takes places after a week of ministerial resignations.
In addition to Smith's departure from the Home Office, communities secretary Hazel Blears has stepped down, as has Cabinet Office minister Tom Watson and children's minister Beverley Hughes.
5 June 2009